Kusuriya no Hitorigoto 2nd Season

The Apothecary Diaries Season 2 / 薬屋のひとりごと第2期 / The Pharmacist's Monologue / Drugstore Soliloquy

Genres: Drama, Historical, Medical, Mystery
Themes: Historical, Medical
Studios: OLM, TOHO animation STUDIO
Producers: Dentsu, Imagica Infos, Nippon Television Network, Shogakukan, Sound Team Don Juan, Square Enix, TOHO animation
Rating: 8.92 / 10
Rank: #20
Popularity: #707
Users Listed: 368,404
Users Scored: 153,387
NSFW: No
Last Updated: 06/13/2025
Aired: January 10, 2025 – July 4, 2025 (Winter)
Type: tv
Source: Light Novel
Age Rating: PG 13
Episodes: 24
Broadcast: Friday at 23:00 (JST)

Synopsis:

Set within the intricate world of an imperial court, the narrative follows Maomao, a woman skilled in both medicinal arts and the subtle applications of poisons. She navigates the complex political landscape by serving the emperor’s consorts, aiding their ladies-in-waiting with literacy and well-being alongside the influential eunuch Jinshi. Maomao's established routine is disrupted by the arrival of a merchant caravan, whose seemingly random occurrences trigger her investigative instincts.

As unsettling patterns emerge from the caravan's trade, Maomao must employ her keen intellect to unravel hidden dangers threatening the court's delicate power dynamics. The series explores themes of loyalty, deception and female agency within a hierarchical society, offering a nuanced portrayal of intrigue and survival in a gilded cage. The atmosphere is one of subtle suspense, blending historical detail with character-driven storytelling.

Trailer:

Streaming Platforms:

Crunchyroll

Episodes:

Episode 1: Maomao and Maomao (Aired: 01/10/2025)
Episode 2: Caravan (Aired: 01/17/2025)
Episode 3: Corpse Fungus (Aired: 01/24/2025)
Episode 4: Mirror (Aired: 01/31/2025)
Episode 5: The Moon Fairy (Aired: 02/07/2025)
... and 19 more episodes

Characters:

Jinshi (Main) - Voice Actors: Ootsuka, Takeo, Tang, Kaiji, Allouf, Julien, Becerril, Diego, Guedes, Douglas, Han, Megumi, Bernard, Ophélie
Maomao (Main) - Voice Actors: Yuuki, Aoi, Lo, Emi, Rault, Émilie, González, Desireé, Patta, Gigi
Ah-Duo (Supporting) - Voice Actors: Kaida, Yuuko, Rial, Monica, Milon, Annie, Ramos, Stela
Ailan (Supporting) - Voice Actors: Ishii, Misa, Moreno, Naya, Attali, Nahla, Guidotti, Kelly, Infante, Elizabeth
Anshi (Supporting) - Voice Actors: Noto, Mamiko, Maréchal, Marie-Eugénie, Lana, Thainá, Ewulu, Cassie
Anshi's Lady-in-waiting (Supporting) - Voice Actors: Ronté, Céline, Kouda, Kaho, Bock, Fernanda
Ayla (Supporting) - Voice Actors: Lynn, Morris, Madeleine, Évanz, Simone
Aylin (Supporting) - Voice Actors: Hara, Yumi, Daviau, Hayden, Beatriz, Anne
Basen (Supporting) - Voice Actors: Tachibana, Tatsumaru, Herlin, Simon, Sousa, Zé, Escamilla, Edward
Emperor (Supporting) - Voice Actors: Endou, Daichi, Mai, Alex, Orsat, Guillaume, Simões, Márcio, Garcia, Andrés
Gaoshun (Supporting) - Voice Actors: Konishi, Katsuyuki, Hom, Alex, Le Minoux, Martial, Perón, Fernando, Ramos, David
Guen (Supporting) - Voice Actors: Kanuka, Mitsuaki, Foronda, Jim, Missoffe, Éric, Rufino, Sérgio, Melgarejo Falconi, Gustavo
Guiyuan (Supporting) - Voice Actors: Tanaka, Takako, Greenshield, Kelly, Mallié, Salomé, Ida, Letícia, Acevedo, Casandra
Gyokuyou (Supporting) - Voice Actors: Tanezaki, Atsumi, Zhang, Molly, Mesquita, Tonia, Contreras, Claudia, Maffren, Ludivine
Haku-u (Supporting) - Voice Actors: Satou, Satomi, Heller, Karl-Line, Bonato, Amanda, Edwards, Kara
Hongniang (Supporting) - Voice Actors: Toyoguchi, Megumi, Cruz, Giovannie, Bellone, Anissa, Ricci, Kate Kelly, Gándara Gutierrez, Stephanie
Jin (Supporting) - Voice Actors: Kumagai, Mirei, Souza, Agda, Temshiv, Kayla
Joka (Supporting) - Voice Actors: Nanami, Hiroki, Flatley, Monica, Moreau, Ninon, Pozatto, Mariana
Kan, Lakan (Supporting) - Voice Actors: Kirimoto, Takuya, Gabay, Bernard, de Almeida, Cláudio Galvan
Kan, Lahan (Supporting) - Voice Actors: Toyonaga, Toshiyuki, Yen, Caleb, Maia, Pedro
Kanan (Supporting) - Voice Actors: Shouji, Umeka
Koku-u (Supporting) - Voice Actors: Ueda, Hitomi, Heller, Karl-Line, Abati, Rúbia, Haruka Ewe, Natalie
Kyou-u (Supporting) - Voice Actors: Fujiwara, Natsumi, Yatco, Anne, Amorim, Luiz Henrique
Lihaku (Supporting) - Voice Actors: Akabane, Kenji, Pacheco, Rafael, Reignoux, Donald, Pimenta, Luis Felipe, Fuentes, Seth
Lihua (Supporting) - Voice Actors: Ishikawa, Yui, Nishimura, Trina, Tilloy, Anne, Helman, Maju, Toriz, Ivett
Lingli (Supporting) - Voice Actors: Tanezaki, Atsumi, Piskor, Monica, Caffagni, Alice
Lishu (Supporting) - Voice Actors: Kino, Hina, Mae, Reshel, Carmes, Rune, Scapin, Izzy, Piedra, Estefanía
Loen (Supporting) - Voice Actors: Kobatake, Masafumi, de Niggro, Carlos
Loulan (Supporting) - Voice Actors: Olea, Vanessa, Seto, Asami, Noiret, Youna, Cristina, Camila, Yeung, Suzie
Luomen (Supporting) - Voice Actors: Yanaka, Hiroshi, Allouf, Bernard, Miller, Stephen, de Carvalho, Paulo Roberto
Madam (Supporting) - Voice Actors: Saitou, Kimiko, Powell, Wendy, Leprince, Isabelle
Meimei (Supporting) - Voice Actors: Han, Megumi, Danae, Rebecca, Honda, Mayumi, Ouaknine, Sophie
Narrator (Supporting) - Voice Actors: Shimamoto, Sumi, Rial, Monica, Massoteau, Anne, Pereira, Zodja
Old Eunuch (Supporting) - Voice Actors: Lafourcade, Daniel, Yasuhara, Yoshito, Vaccari, Hélio, Williams, Kent
Onsou (Supporting) - Voice Actors: Egoshi, Akinori, Sauer, André
Pairin (Supporting) - Voice Actors: Koshimizu, Ami, Strange, Ciarán, Marchese, Sabrina, Swirski, Mariana
Renpu (Supporting) - Voice Actors: Fushimi, Haruka, Fuentes, Mariana
Rikuson (Supporting) - Voice Actors: Uchiyama, Kouki, Sover, Yoann, Rocha, Kadu
Seki-u (Supporting) - Voice Actors: Itou, Miku, Heller, Karl-Line, Mascarenhas, Bruna
Shenlü (Supporting) - Voice Actors: Katsuki, Masako, Viana, Tânia
Shenmei (Supporting) - Voice Actors: Fukami, Rica, Calvello, Jessica, Azevedo, Sandra Mara, Rondeleux, Anne
Shin (Supporting) - Voice Actors: Kinoshita, Sayaka, Bassi, Iris, Garrett, Morgan, Wellong, Corinne
Shishou (Supporting) - Voice Actors: Cho, Pistorio, Pierre-François, Cavaglieri, Thonny
Shisui (Supporting) - Voice Actors: Seto, Asami, Yeung, Suzie, Cristina, Camila, Noiret, Youna
Son (Supporting) - Voice Actors: Akasaki, Chinatsu
Sourin (Supporting) - Voice Actors: Kawamura, Rie
Suirei (Supporting) - Voice Actors: Nazuka, Kaori, Laux, Veronica, Bodê, Andressa, Orsat, Alice
Suiren (Supporting) - Voice Actors: Doi, Mika, Kaida, Yuuko, Victória, Cláudia, Le Coutour, Anne
Suusuu (Supporting) - Voice Actors: Takahashi, Saki, Caffagni, Alice, Carmes, Rune
Ukyou (Supporting) - Voice Actors: Hasegawa, Yoshiaki, Seung, Oscar, Minéo, Sébastien, Berro, Bernardo
Xiaolan (Supporting) - Voice Actors: Kuno, Misaki, Han, Bree, Lauzeray Gishi, Anna, Cavalcante, Isa, Ornelas, Fernanda
Yinghua (Supporting) - Voice Actors: Hikisaka, Rie, Cruz, Kelsey, Hauguel, Amandine, de Barros, Marcela, Lobo, Ana
You (Supporting) - Voice Actors: Kusumi, Rin, Lauzeray Gishi, Anna

Staff:

Fujimura, Tomoko (Producer)
Hirahara, Yuito (Producer)
Iwata, Takao (Producer)
Morishita, Katsuji (Producer)
Okamoto, Junya (Producer)
Sumitomo, Eiji (Producer)
Tachibana, Yukari (Producer)
Yazawa, Izumi (Producer)
Kirita, Yoshinobu (Assistant Producer)
Onoue, Taiki (Assistant Producer)
Fudesaka, Akimi (Director, Episode Director, Storyboard)
Naganuma, Norihiro (Director, Series Composition)
Hata, Shouji (Sound Director)
Akatsuki, You (Episode Director)
Asai, Kaho (Episode Director)
Asaki, Yukihiko (Episode Director, Storyboard)
Chidphong, Limthong (Episode Director)
China (Episode Director, Storyboard, Key Animation)
Hiraike, Yoshimasa (Episode Director, Storyboard)
Itoga, Shintarou (Episode Director)
Kawabata, Erkin (Episode Director, Storyboard, Animation Director)
Kinome, Yuu (Episode Director)
Komamiya, Wazuka (Episode Director, Storyboard, Key Animation, Animation Director)
Koremoto, Akira (Episode Director, Storyboard)
Matsunaga, Masahiro (Episode Director)
Misu Yamaneko (Episode Director)
Nakagawa, Wataru (Episode Director, Storyboard, Assistant Director)
Nakano, Tsuyoshi (Episode Director)
Nakata, Ayaka (Episode Director, Storyboard)
Oh, Jin-Gu (Episode Director)
Oowada, Jun (Episode Director, Storyboard)
Tanimoto, Mayu (Episode Director, Storyboard)
Yano, Takanori (Episode Director)
Botsu, Azumi (Script)
Chiba, Misuzu (Script)
Kakihara, Yuuko (Script)
Ogawa, Hitomi (Script)
Hayashi, Naotaka (Storyboard)
Nihei, Yuuichi (Storyboard)
Oohara, Minoru (Storyboard)
Takahashi, Naohito (Storyboard)
EIGO (Theme Song Lyrics)
Hirai, Dai (Theme Song Arrangement, Theme Song Composition, Theme Song Lyrics, Theme Song Performance)
Ikuta, Lilas (Theme Song Performance, Theme Song Composition, Theme Song Lyrics)
KOHD (Theme Song Arrangement)
Kubota, Singo (Theme Song Arrangement)
Mrs. GREEN APPLE (Theme Song Performance)
Nishi, Haruhito (Theme Song Arrangement)
Ohmori, Motoki (Theme Song Composition, Theme Song Lyrics, Theme Song Arrangement)
Omoinotake (Theme Song Arrangement, Theme Song Performance)
... and 95 more staff

News:

'Kusuriya no Hitorigoto' Anime Sequel Announced (07/05/2025)
Winter 2025 Simulcast List [Update 2/23] (01/01/2025)
Winter 2025 Preview (12/19/2024)
'Kusuriya no Hitorigoto' 2nd Season Unveils New Staff, Teaser Promo for Winter 2025 (10/22/2024)
'Kusuriya no Hitorigoto' Second Season Announced (03/23/2024)

Forum Topics:

External Links:

Related Anime/Manga:

Kusuriya no Hitorigoto (anime - Prequel)
Kusuriya no Hitorigoto (Zoku-hen) (anime - Sequel)
Kusuriya no Hitorigoto (manga - Adaptation)
Kusuriya no Hitorigoto: Maomao no Koukyuu Nazotoki Techou (manga - Adaptation)
Kusuriya no Hitorigoto (manga - Adaptation)
Maomao no Hitorigoto 2nd Season (anime - Other)